Acute coronary syndrome (ACS) group includes a variety of clinical conditions that arise as a result of acute ischemia and / or myocardial necrosis which is usually the cause of acute coronary lesions, caused by ruptured atherosclerotic plaque in coronary atreriji with associated inflammation, thrombosis, vasoconstriction and microembolization.
Acute coronary syndrome can be manifested as: unstable angina pectoris, acute myocardial infarction with ST-segment elevation or sudden cardiac death.
According to the tenth revision of International Classification of Diseases (MKB10) code of acute myocardial infarction in 121, repeated acute myocardial infarction I22 and unstable angina pectoris I20.0.
As the most severe form of ischemic heart disease (CHD), acute coronary syndrome is one of the most common cause of emergency admission to hospital and sudden death in the developed parts of the world, and in recent decades in developing countries.
According to the World Health Organization (WHO), the annual average in the world of acute myocardial infarction diagnosed 6 million people, with lethal outcome occurs in more than 25% of cases.
Previous research in the world and have provided us valuable clinical, but no epidemiological data on the incidence of acute coronary syndrome in the population.
Epidemiological, population studies of acute coronary syndromes are rare. One of them is a Danish cohort study with more than 130,000 people aged 30 to 69 years which is estimated that crude incidence rate of acute coronary syndrome was 234 per 100,000.
In our country since 1980. The law regulates the obligation of keeping the Register of coronary heart disease based on the Plan of statistical research for the Republic (Official Gazette of SRS no. 32/79).
However, an inadequate set of data on the application form, imprecise methodological instruction, insufficient training of personnel for maintaining the Registry, and the lack of IT support have resulted subregistraciju new cases of coronary heart disease.
Thus, for example. in Serbia, to the end of the 90s the number of reported persons with coronary disease was far lower than the average number of deaths and as much as 20 times lower than expected number of patients with ischemic heart disease.
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